Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM56285
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
50000±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM56285
Synonyms:
2-(4-chlorophenyl)-N-(5-keto-7,7-dimethyl-6,8-dihydroquinazolin-2-yl)acetamide | 2-(4-chlorophenyl)-N-(7,7-dimethyl-5-oxidanylidene-6,8-dihydroquinazolin-2-yl)ethanamide | 2-(4-chlorophenyl)-N-(7,7-dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)acetamide | MLS000109679 | SMR000105619 | cid_878804
Type:
Small organic molecule
Emp. Form.:
C18H18ClN3O2
Mol. Mass.:
343.807
SMILES:
CC1(C)CC(=O)c2cnc(NC(=O)Cc3ccc(Cl)cc3)nc2C1
Structure:
Search PDB for entries with ligand similarity: