Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM56573
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
50000±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM56573
Synonyms:
1-[2-(4-Ethoxy-benzylsulfanyl)-ethyl]-3-phenyl-thiourea | 1-[2-[(4-ethoxybenzyl)thio]ethyl]-3-phenyl-thiourea | 1-[2-[(4-ethoxyphenyl)methylsulfanyl]ethyl]-3-phenyl-thiourea | 1-[2-[(4-ethoxyphenyl)methylsulfanyl]ethyl]-3-phenylthiourea | 1-[2-[(4-ethoxyphenyl)methylthio]ethyl]-3-phenylthiourea | MLS000590000 | SMR000217179 | cid_1905667
Type:
Small organic molecule
Emp. Form.:
C18H22N2OS2
Mol. Mass.:
346.51
SMILES:
CCOc1ccc(CSCCNC(=S)Nc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: