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Target
Large T antigen
Ligand
BDBM50247
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits
EC50
15210±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits PubChem Bioassay (2009)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM50247
Synonyms:
(5Z)-5-({5-[(2-furylmethyl)thio]-2-furyl}methylene)-2-thioxo-1,3-thiazolidin-4-one | (5Z)-5-[[5-(2-furanylmethylthio)-2-furanyl]methylidene]-2-sulfanylidene-4-thiazolidinone | (5Z)-5-[[5-(2-furfurylthio)-2-furyl]methylene]-2-thioxo-thiazolidin-4-one | (5Z)-5-[[5-(furan-2-ylmethylsulfanyl)furan-2-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | MLS000582442 | SMR000206428 | cid_12005023
Type:
Small organic molecule
Emp. Form.:
C13H9NO3S3
Mol. Mass.:
323.41
SMILES:
SC1=NC(=O)C(S1)=Cc1ccc(SCc2ccco2)o1 |w:7.8,t:1|
Structure:
Search PDB for entries with ligand similarity: