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Target
Large T antigen
Ligand
BDBM59002
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits
EC50
13750±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits PubChem Bioassay (2009)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM59002
Synonyms:
(3-bromo-4-ethoxy-5-methoxy-benzyl)-(4-morpholinophenyl)amine | (3-bromo-4-ethoxy-5-methoxybenzyl)[4-(4-morpholinyl)phenyl]amine | MLS000684106 | N-[(3-bromanyl-4-ethoxy-5-methoxy-phenyl)methyl]-4-morpholin-4-yl-aniline | N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-4-(4-morpholinyl)aniline | N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-4-morpholin-4-ylaniline | SMR000295746 | cid_979593
Type:
Small organic molecule
Emp. Form.:
C20H25BrN2O3
Mol. Mass.:
421.328
SMILES:
CCOc1c(Br)cc(CNc2ccc(cc2)N2CCOCC2)cc1OC
Structure:
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