Reaction Details Report a problem with these data
Target
M17 leucyl aminopeptidase
Ligand
BDBM51988
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
IC50
11550±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay (2009)[AID] 
Target
Name:
M17 leucyl aminopeptidase
Synonyms:
leucine aminopeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67834.32
Organism:
Plasmodium falciparum 3D7
Description:
gi_124809582
Residue:
605
Sequence:
MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKKNINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSKYADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAL
  
Inhibitor
Name:
BDBM51988
Synonyms:
3-(4-tert-butylbenzyl)oxy-2-thenoic acid | 3-[(4-tert-butylphenyl)methoxy]-2-thiophenecarboxylic acid | 3-[(4-tert-butylphenyl)methoxy]thiophene-2-carboxylic acid | 3-{[4-(tert-butyl)benzyl]oxy}-2-thiophenecarboxylic acid | MLS000755881 | SMR000337910 | cid_1483473
Type:
Small organic molecule
Emp. Form.:
C16H18O3S
Mol. Mass.:
290.377
SMILES:
CC(C)(C)c1ccc(COc2ccsc2C(O)=O)cc1
Structure:
Search PDB for entries with ligand similarity: