Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM50647
Substrate
n/a
Meas. Tech.
uHTS absorbance assay for the identification of compounds that inhibit VHR1.
IC50
980±n/a nM
Citation
 PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM50647
Synonyms:
2,3,4,5-tetrahydroxy-6-benzo[7]annulenone | 2,3,4,5-tetrahydroxybenzo[7]annulen-6-one | 2,3,4,5-tetrahydroxybenzocyclohepten-6-one | 2,3,4,5-tetrakis(oxidanyl)benzo[7]annulen-6-one | MLS000738105 | SMR000393869 | cid_5281571
Type:
Small organic molecule
Emp. Form.:
C11H8O5
Mol. Mass.:
220.1782
SMILES:
Oc1cc2cccc(=O)c(O)c2c(O)c1O
Structure:
Search PDB for entries with ligand similarity: