Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61354
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61354
Synonyms:
2-(3-methyl-1-pyridin-1-iumyl)-1-phenylethanone;bromide | 2-(3-methylpyridin-1-ium-1-yl)-1-phenyl-ethanone;bromide | 2-(3-methylpyridin-1-ium-1-yl)-1-phenylethanone;bromide | 3-methyl-1-(2-oxo-2-phenylethyl)pyridinium | MLS001195138 | SMR000554477 | cid_12247929
Type:
Small organic molecule
Emp. Form.:
C14H14NO
Mol. Mass.:
212.2665
SMILES:
Cc1ccc[n+](CC(=O)c2ccccc2)c1
Structure:
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