Reaction Details Report a problem with these data
Target
Serine/threonine-protein phosphatase
Ligand
BDBM33124
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
29469±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM33124
Synonyms:
2-Chloro-3-[4-(2-nitro-phenyl)-piperazin-1-yl]-[1,4]naphthoquinone | 2-chloranyl-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)-1-piperazinyl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)piperazino]-1,4-naphthoquinone | MLS000588199 | SMR000220218 | cid_4561725
Type:
Small organic molecule
Emp. Form.:
C20H16ClN3O4
Mol. Mass.:
397.812
SMILES:
[O-][N+](=O)c1ccccc1N1CCN(CC1)C1=C(Cl)C(=O)c2ccccc2C1=O |c:17|
Structure:
Search PDB for entries with ligand similarity: