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Target
Mu-type opioid receptor
Ligand
BDBM64857
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1)
IC50
6947±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM64857
Synonyms:
5-methoxy-4-(4-methylphenyl)sulfanyl-2-pyridin-2-yl-pyrimidine | 5-methoxy-4-(4-methylphenyl)sulfanyl-2-pyridin-2-ylpyrimidine | 5-methoxy-4-(p-tolylthio)-2-(2-pyridyl)pyrimidine | 5-methoxy-4-[(4-methylphenyl)thio]-2-(2-pyridinyl)pyrimidine | MLS000692232 | SMR000333903 | cid_1470825 | methyl 4-[(4-methylphenyl)sulfanyl]-2-(2-pyridinyl)-5-pyrimidinyl ether
Type:
Small organic molecule
Emp. Form.:
C17H15N3OS
Mol. Mass.:
309.386
SMILES:
COc1cnc(nc1Sc1ccc(C)cc1)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: