Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM66107
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase
IC50
38774±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM66107
Synonyms:
7-(diethylamino)-2-keto-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxidanylidene-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxo-1-benzopyran-3-carboxaldehyde | 7-(diethylamino)-2-oxochromene-3-carbaldehyde | 7-Diethylamino-2-oxo-2H-chromene-3-carbaldehyde | MLS000529175 | SMR000121650 | cid_143191
Type:
Small organic molecule
Emp. Form.:
C14H15NO3
Mol. Mass.:
245.2738
SMILES:
CCN(CC)c1ccc2cc(C=O)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: