Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM66107
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
IC50
26747±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29494.42
Organism:
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Description:
gi_60115532
Residue:
269
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGESGNYG
  
Inhibitor
Name:
BDBM66107
Synonyms:
7-(diethylamino)-2-keto-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxidanylidene-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxo-1-benzopyran-3-carboxaldehyde | 7-(diethylamino)-2-oxochromene-3-carbaldehyde | 7-Diethylamino-2-oxo-2H-chromene-3-carbaldehyde | MLS000529175 | SMR000121650 | cid_143191
Type:
Small organic molecule
Emp. Form.:
C14H15NO3
Mol. Mass.:
245.2738
SMILES:
CCN(CC)c1ccc2cc(C=O)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: