Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66324
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66324
Synonyms:
(3E)-1-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methoxy]-3-[[(2,4-dichlorobenzyl)oxyamino]methylene]urea | 1-[[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea | 1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea | 1-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methoxy]-3-[[(2,4-dichlorobenzyl)oxyamino]methylene]urea | 1-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea | MLS000539628 | N-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methoxy}-N-({[(2,4-dichlorobenzyl)oxy]imino}methyl)urea | SMR000125286 | cid_3409513
Type:
Small organic molecule
Emp. Form.:
C16H12Cl3F3N4O3
Mol. Mass.:
471.646
SMILES:
FC(F)(F)c1cnc(CONC(=O)NC=NOCc2ccc(Cl)cc2Cl)c(Cl)c1 |w:15.15|
Structure:
Search PDB for entries with ligand similarity: