Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM57399
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
3668±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM57399
Synonyms:
2-[2-ethoxy-4-(2-nitrovinyl)phenoxy]-N-(2-methylphenyl)acetamide | 2-[2-ethoxy-4-[(Z)-2-nitroethenyl]phenoxy]-N-(2-methylphenyl)acetamide | 2-[2-ethoxy-4-[(Z)-2-nitroethenyl]phenoxy]-N-(2-methylphenyl)ethanamide | 2-[2-ethoxy-4-[(Z)-2-nitrovinyl]phenoxy]-N-(o-tolyl)acetamide | MLS000575834 | SMR000196870 | cid_2295300
Type:
Small organic molecule
Emp. Form.:
C19H20N2O5
Mol. Mass.:
356.3725
SMILES:
CCOc1cc(\C=C/[N+]([O-])=O)ccc1OCC(=O)Nc1ccccc1C
Structure:
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