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Target
Bcl-2-like protein 11
Ligand
BDBM57528
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM57528
Synonyms:
2-furancarboxylic acid [3-[[[4-anilino-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazinylidene]methyl]phenyl] ester | Furan-2-carboxylic acid 3-[(4-morpholin-4-yl-6-phenylamino-[1,3,5]triazin-2-yl)-hydrazonomethyl]-phenyl ester | MLS000560358 | SMR000175363 | [3-[[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)hydrazinylidene]methyl]phenyl] furan-2-carboxylate | [3-[[(4-morpholin-4-yl-6-phenylazanyl-1,3,5-triazin-2-yl)hydrazinylidene]methyl]phenyl] furan-2-carboxylate | cid_3111016 | furan-2-carboxylic acid [3-[[(4-anilino-6-morpholino-s-triazin-2-yl)hydrazono]methyl]phenyl] ester
Type:
Small organic molecule
Emp. Form.:
C25H23N7O4
Mol. Mass.:
485.4946
SMILES:
O=C(Oc1cccc(CN=Nc2nc(Nc3ccccc3)nc(n2)N2CCOCC2)c1)c1ccco1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: