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Target
Bcl-2-like protein 11
Ligand
BDBM66438
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
9230±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66438
Synonyms:
(2-{[2-(3,4-Dimethyl-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoquinolin-(4E)-ylidenemethyl]-amino}-thiazol-4-yl)-acetic acid ethyl ester | 2-[2-[[(E)-[2-(3,4-dimethylphenyl)-1,3-diketo-4-isoquinolylidene]methyl]amino]thiazol-4-yl]acetic acid ethyl ester | 2-[2-[[(E)-[2-(3,4-dimethylphenyl)-1,3-dioxo-4-isoquinolinylidene]methyl]amino]-4-thiazolyl]acetic acid ethyl ester | MLS000331794 | SMR000221269 | cid_6015159 | ethyl 2-[2-[[(E)-[2-(3,4-dimethylphenyl)-1,3-bis(oxidanylidene)isoquinolin-4-ylidene]methyl]amino]-1,3-thiazol-4-yl]ethanoate | ethyl 2-[2-[[(E)-[2-(3,4-dimethylphenyl)-1,3-dioxoisoquinolin-4-ylidene]methyl]amino]-1,3-thiazol-4-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C25H23N3O4S
Mol. Mass.:
461.533
SMILES:
CCOC(=O)Cc1csc(N=Cc2c(O)n(-c3ccc(C)c(C)c3)c(=O)c3ccccc23)n1 |w:10.9|
Structure:
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