Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66472
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66472
Synonyms:
2-[(2,6-dimethylphenyl)carbamothioylamino]-N-(furan-2-ylmethyl)benzamide | 2-[(2,6-dimethylphenyl)thiocarbamoylamino]-N-(2-furfuryl)benzamide | 2-[[(2,6-dimethylanilino)-sulfanylidenemethyl]amino]-N-(2-furanylmethyl)benzamide | MLS000335781 | SMR000253535 | cid_2462681
Type:
Small organic molecule
Emp. Form.:
C21H21N3O2S
Mol. Mass.:
379.475
SMILES:
Cc1cccc(C)c1NC(=S)Nc1ccccc1C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: