Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66782
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66782
Synonyms:
1-(4-chlorophenyl)-3-[2-(4-methyl-1-piperazinyl)ethyl]urea | 1-(4-chlorophenyl)-3-[2-(4-methylpiperazin-1-yl)ethyl]urea | 1-(4-chlorophenyl)-3-[2-(4-methylpiperazino)ethyl]urea | MLS001197592 | N-(4-chlorophenyl)-N'-[2-(4-methylpiperazin-1-yl)ethyl]urea | SMR000559951 | cid_22430294
Type:
Small organic molecule
Emp. Form.:
C14H21ClN4O
Mol. Mass.:
296.796
SMILES:
CN1CCN(CCNC(=O)Nc2ccc(Cl)cc2)CC1
Structure:
Search PDB for entries with ligand similarity: