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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43676
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1)
EC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1): luminescence-based cell-based dose response assay for STAT3 activators PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43676
Synonyms:
MLS000065715 | N-(1,3-benzothiazol-2-yl)-5-methyl-2-thiophenecarboxamide | N-(1,3-benzothiazol-2-yl)-5-methyl-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-5-methylthiophene-2-carboxamide | N-1,3-benzothiazol-2-yl-5-methyl-2-thiophenecarboxamide | SMR000080382 | cid_1245575
Type:
Small organic molecule
Emp. Form.:
C13H10N2OS2
Mol. Mass.:
274.361
SMILES:
Cc1ccc(s1)C(=O)Nc1nc2ccccc2s1
Structure:
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