Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43694
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1)
EC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1): luminescence-based cell-based dose response assay for STAT3 activators PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43694
Synonyms:
MLS000578308 | N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide | N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanamide | N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide | SMR000198208 | cid_1281370
Type:
Small organic molecule
Emp. Form.:
C18H14N4OS3
Mol. Mass.:
398.525
SMILES:
Cc1nnc(SCC(=O)Nc2ccc(cc2)-c2nc3ccccc3s2)s1
Structure:
Search PDB for entries with ligand similarity: