Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM76054
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76054
Synonyms:
3-[1-[2-(2-fluorophenyl)-1-oxoethyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-one | 3-[1-[2-(2-fluorophenyl)acetyl]-4-piperidyl]-5-phenyl-1,3,4-oxadiazol-2-one | 3-[1-[2-(2-fluorophenyl)acetyl]piperidin-4-yl]-5-phenyl-1,3,4-oxadiazol-2-one | 3-[1-[2-(2-fluorophenyl)ethanoyl]piperidin-4-yl]-5-phenyl-1,3,4-oxadiazol-2-one | MLS-0437150.0001 | cid_23612542
Type:
Small organic molecule
Emp. Form.:
C21H20FN3O3
Mol. Mass.:
381.4002
SMILES:
Fc1ccccc1CC(=O)N1CCC(CC1)n1nc(oc1=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: