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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78525
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
9906±426 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78525
Synonyms:
MLS000032400 | N-(2-Methoxy-phenyl)-2-[5-(2-methyl-furan-3-yl)-4-phenethyl-4H-[1,2,4]triazol-3-ylsulfanyl]-acetamide | N-(2-methoxyphenyl)-2-[[5-(2-methyl-3-furanyl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetamide | N-(2-methoxyphenyl)-2-[[5-(2-methyl-3-furyl)-4-phenethyl-1,2,4-triazol-3-yl]thio]acetamide | N-(2-methoxyphenyl)-2-[[5-(2-methylfuran-3-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide | N-(2-methoxyphenyl)-2-[[5-(2-methylfuran-3-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethanamide | SMR000005720 | cid_655644
Type:
Small organic molecule
Emp. Form.:
C24H24N4O3S
Mol. Mass.:
448.537
SMILES:
COc1ccccc1NC(=O)CSc1nnc(-c2ccoc2C)n1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: