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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78860
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
8940±314 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78860
Synonyms:
4-[(2-ketobenzo[cd]indol-1-yl)methyl]benzohydrazide | 4-[(2-oxidanylidenebenzo[cd]indol-1-yl)methyl]benzohydrazide | 4-[(2-oxo-1-benzo[cd]indolyl)methyl]benzohydrazide | 4-[(2-oxobenzo[cd]indol-1-yl)methyl]benzohydrazide | MLS000517087 | SMR000343265 | cid_2435396
Type:
Small organic molecule
Emp. Form.:
C19H15N3O2
Mol. Mass.:
317.3413
SMILES:
NNC(=O)c1ccc(CN2C(=O)c3cccc4cccc2c34)cc1
Structure:
Search PDB for entries with ligand similarity: