Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM63629
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
4670±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM63629
Synonyms:
4,5-bis(bromanyl)-2-(4-methylphenyl)pyridazin-3-one | 4,5-dibromo-2-(4-methylphenyl)-3(2H)-pyridazinone | 4,5-dibromo-2-(4-methylphenyl)-3-pyridazinone | 4,5-dibromo-2-(4-methylphenyl)pyridazin-3-one | 4,5-dibromo-2-(p-tolyl)pyridazin-3-one | MLS000720992 | SMR000335544 | cid_1487485
Type:
Small organic molecule
Emp. Form.:
C11H8Br2N2O
Mol. Mass.:
344.002
SMILES:
Cc1ccc(cc1)-n1ncc(Br)c(Br)c1=O
Structure:
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