Reaction Details Report a problem with these data
Target
Tropomyosin alpha-1 chain
Ligand
BDBM32010
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
3708±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM32010
Synonyms:
(4Z)-4-[[4-(dimethylamino)anilino]methylene]-2-phenyl-2-oxazolin-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-1,3-oxazol-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-5-oxazolone | (4Z)-4-[[[4-(dimethylamino)phenyl]amino]methylidene]-2-phenyl-1,3-oxazol-5-one | 4-[1-(4-Dimethylamino-phenylamino)-meth-(Z)-ylidene]-2-phenyl-4H-oxazol-5-one | MLS000077184 | SMR000009577 | cid_5378674
Type:
Small organic molecule
Emp. Form.:
C18H17N3O2
Mol. Mass.:
307.3465
SMILES:
CN(C)c1ccc(cc1)N=Cc1nc(oc1O)-c1ccccc1 |w:9.9|
Structure:
Search PDB for entries with ligand similarity: