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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79674
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
3911±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79674
Synonyms:
MLS000579105 | N'-[(3-oxo-1-benzothien-2(3H)-ylidene)methyl]benzohydrazide | N'-[(Z)-(3-ketobenzothiophen-2-ylidene)methyl]benzohydrazide | N'-[(Z)-(3-oxidanylidene-1-benzothiophen-2-ylidene)methyl]benzohydrazide | N'-[(Z)-(3-oxo-1-benzothiophen-2-ylidene)methyl]benzohydrazide | SMR000186694 | cid_5656784
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2S
Mol. Mass.:
296.344
SMILES:
Oc1c(C=NNC(=O)c2ccccc2)sc2ccccc12 |w:4.4|
Structure:
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