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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79699
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
1137±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79699
Synonyms:
(5E)-5-(2,5-dimethoxy-4-pyrrolidino-benzylidene)-2-thioxo-4-imidazolidinone | (5E)-5-[(2,5-dimethoxy-4-pyrrolidin-1-yl-phenyl)methylidene]-2-sulfanylidene-imidazolidin-4-one | (5E)-5-[(2,5-dimethoxy-4-pyrrolidin-1-ylphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one | (5E)-5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-2-sulfanylidene-4-imidazolidinone | 5-[2,5-dimethoxy-4-(1-pyrrolidinyl)benzylidene]-2-thioxo-4-imidazolidinone | MLS000699213 | SMR000229322 | cid_839760
Type:
Small organic molecule
Emp. Form.:
C16H19N3O3S
Mol. Mass.:
333.405
SMILES:
COc1cc(N2CCCC2)c(OC)cc1\C=C1\NC(=S)NC1=O
Structure:
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