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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79707
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
3734±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79707
Synonyms:
MLS000718088 | N-[(3-cyano-6-propyl-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)carbamothioyl]benzamide | N-[(3-cyano-6-propyl-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)thiocarbamoyl]benzamide | N-[[(3-cyano-6-propyl-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)amino]-sulfanylidenemethyl]benzamide | SMR000279856 | cid_1130140
Type:
Small organic molecule
Emp. Form.:
C19H20N4OS2
Mol. Mass.:
384.518
SMILES:
CCCN1CCc2c(C1)sc(NC(=S)NC(=O)c1ccccc1)c2C#N
Structure:
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