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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79709
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
1548±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79709
Synonyms:
(5Z)-1,3-dimethyl-5-(3-methyl-4-pyrrolidino-benzylidene)-2-thioxo-4-imidazolidinone | (5Z)-1,3-dimethyl-5-[(3-methyl-4-pyrrolidin-1-yl-phenyl)methylidene]-2-sulfanylidene-imidazolidin-4-one | (5Z)-1,3-dimethyl-5-[(3-methyl-4-pyrrolidin-1-ylphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one | (5Z)-1,3-dimethyl-5-[[3-methyl-4-(1-pyrrolidinyl)phenyl]methylidene]-2-sulfanylidene-4-imidazolidinone | 1,3-dimethyl-5-[3-methyl-4-(1-pyrrolidinyl)benzylidene]-2-thioxo-4-imidazolidinone | MLS000663843 | SMR000292355 | cid_891056
Type:
Small organic molecule
Emp. Form.:
C17H21N3OS
Mol. Mass.:
315.433
SMILES:
CN1C(=S)N(C)\C(=C/c2ccc(N3CCCC3)c(C)c2)C1=O
Structure:
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