Reaction Details Report a problem with these data
Target
Tropomyosin alpha-1 chain
Ligand
BDBM66124
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
1438±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM66124
Synonyms:
5-(4-nitrophenyl)-2-furaldehyde methyl(phenyl)hydrazone | MLS001164362 | N-methyl-N-[[5-(4-nitrophenyl)-2-furanyl]methylideneamino]aniline | N-methyl-N-[[5-(4-nitrophenyl)furan-2-yl]methylideneamino]aniline | SMR000496563 | cid_2848856 | methyl-[[5-(4-nitrophenyl)-2-furyl]methyleneamino]-phenyl-amine
Type:
Small organic molecule
Emp. Form.:
C18H15N3O3
Mol. Mass.:
321.33
SMILES:
CN(\N=C\c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: