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Target
C-C chemokine receptor type 6
Ligand
BDBM79985
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
21700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM79985
Synonyms:
1-(3-methylphenyl)-3-[(5-nitro-2-thiophenyl)methylideneamino]thiourea | 1-(3-methylphenyl)-3-[(5-nitrothiophen-2-yl)methylideneamino]thiourea | 1-(m-tolyl)-3-[(5-nitro-2-thienyl)methyleneamino]thiourea | MLS000553380 | SMR000175434 | cid_693266
Type:
Small organic molecule
Emp. Form.:
C13H12N4O2S2
Mol. Mass.:
320.39
SMILES:
Cc1cccc(NC(=S)NN=Cc2ccc(s2)[N+]([O-])=O)c1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: