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Target
C-C chemokine receptor type 6
Ligand
BDBM80091
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
15500±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80091
Synonyms:
MLS002701692 | SMR001565290 | [4-[(Z)-[3-[(dimethylamino)methyl]-2-oxidanylidene-cyclopentylidene]methyl]phenoxy]methyl propanoate;hydrochloride | [4-[(Z)-[3-[(dimethylamino)methyl]-2-oxocyclopentylidene]methyl]phenoxy]methyl propanoate;hydrochloride | cid_21141938 | propanoic acid [4-[(Z)-[3-[(dimethylamino)methyl]-2-oxocyclopentylidene]methyl]phenoxy]methyl ester;hydrochloride | propionic acid [4-[(Z)-[3-[(dimethylamino)methyl]-2-keto-cyclopentylidene]methyl]phenoxy]methyl ester;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C19H25NO4
Mol. Mass.:
331.4061
SMILES:
CCC(=O)OCOc1ccc(C=C2CCC(CN(C)C)C2=O)cc1 |w:11.10|
Structure:
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