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Target
C-C chemokine receptor type 6
Ligand
BDBM80093
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
47600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80093
Synonyms:
4-chlorobenzoic acid [4-[(E)-[3-[(dimethylamino)methyl]-2-keto-cyclohexylidene]methyl]phenyl] ester;hydrochloride | 4-chlorobenzoic acid [4-[(E)-[3-[(dimethylamino)methyl]-2-oxocyclohexylidene]methyl]phenyl] ester;hydrochloride | MLS002702440 | SMR001566002 | [4-[(E)-[3-[(dimethylamino)methyl]-2-oxidanylidene-cyclohexylidene]methyl]phenyl] 4-chloranylbenzoate;hydrochloride | [4-[(E)-[3-[(dimethylamino)methyl]-2-oxocyclohexylidene]methyl]phenyl] 4-chlorobenzoate;hydrochloride | cid_5470076
Type:
Small organic molecule
Emp. Form.:
C23H24ClNO3
Mol. Mass.:
397.895
SMILES:
CN(C)CC1CCCC(=Cc2ccc(OC(=O)c3ccc(Cl)cc3)cc2)C1=O |w:9.9|
Structure:
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