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Target
D(1A) dopamine receptor
Ligand
BDBM81487
Substrate
n/a
Ki
360±n/a nM
Comments
PDSP_540
Citation
 Burt, DR; Creese, I; Snyder, SH Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes. Mol Pharmacol 12:800-12 (1976) [PubMed] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49330.65
Organism:
BOVINE
Description:
DOPAMINE D1 DRD1 BOVINE::Q95136
Residue:
446
Sequence:
MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM81487
Synonyms:
CAS_10457-91-7 | CLOFLUPEROL | NSC_25293
Type:
Small organic molecule
Emp. Form.:
C22H22ClF4NO2
Mol. Mass.:
443.862
SMILES:
OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)c(c1)C(F)(F)F
Structure:
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