Reaction Details
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Report a problem with these dataTarget
Neuropeptides B/W receptor type 1
Ligand
BDBM50019574
Substrate
n/a
Ki
5000±n/a nM
Comments
PDSP_592
Citation
O'Dowd, BF; Scheideler, MA; Nguyen, T; Cheng, R; Rasmussen, JS; Marchese, A; Zastawny, R; Heng, HH; Tsui, LC; Shi, X The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain. Genomics 28:84-91 (1995) [PubMed] Article More Info.:
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
Inhibitor
Name:
BDBM50019574
Synonyms:
CHEMBL406014 | CTOP | D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2(CTOP)
Type:
Small organic molecule
Emp. Form.:
C50H67N11O11S2
Mol. Mass.:
1062.264
SMILES:
C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@H](NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O
Structure:
