Reaction Details Report a problem with these data
Target
Hrh3 protein
Ligand
BDBM22888
Substrate
n/a
Ki
68±n/a nM
Comments
PDSP_445
Citation
 Ligneau, X; Garbarg, M; Vizuete, ML; Diaz, J; Purand, K; Stark, H; Schunack, W; Schwartz, JC [125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors. J Pharmacol Exp Ther 271:452-9 (1994) [PubMed] 
Target
Name:
Hrh3 protein
Synonyms:
HISTAMINE H3 | HRH3 | Hrh3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37860.96
Organism:
RAT
Description:
Q5PPG3
Residue:
344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
  
Inhibitor
Name:
BDBM22888
Synonyms:
1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | Burimamide | CHEMBL12160
Type:
Small organic molecule
Emp. Form.:
C9H16N4S
Mol. Mass.:
212.315
SMILES:
CNC(=S)NCCCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: