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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM82711
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
6270±268 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM82711
Synonyms:
MLS000581278 | N-(4-{[2-(3-phenylpropanoyl)hydrazino]carbonyl}phenyl)benzamide | N-[4-[(3-phenylpropanoylamino)carbamoyl]phenyl]benzamide | N-[4-[(hydrocinnamoylamino)carbamoyl]phenyl]benzamide | N-[4-[oxo-[(1-oxo-3-phenylpropyl)hydrazo]methyl]phenyl]benzamide | SMR000199892 | cid_2207747
Type:
Small organic molecule
Emp. Form.:
C23H21N3O3
Mol. Mass.:
387.4311
SMILES:
O=C(CCc1ccccc1)NNC(=O)c1ccc(NC(=O)c2ccccc2)cc1
Structure:
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