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Target
Cysteine protease ATG4B
Ligand
BDBM47570
Substrate
n/a
Meas. Tech.
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B Set 2
IC50
5400±n/a nM
Citation
 PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Cysteine protease ATG4B
Synonyms:
APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44279.79
Organism:
Homo sapiens (Human)
Description:
gi_47132611
Residue:
393
Sequence:
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
  
Inhibitor
Name:
BDBM47570
Synonyms:
(1Z)-1-[[2-[4-(1H-imidazol-2-yl)phthalazin-1-yl]hydrazinyl]methylidene]naphthalen-2-one | (1Z)-1-[[N'-[4-(1H-imidazol-2-yl)phthalazin-1-yl]hydrazino]methylene]naphthalen-2-one | (1Z)-1-[[[4-(1H-imidazol-2-yl)-1-phthalazinyl]hydrazo]methylidene]-2-naphthalenone | MLS000564044 | SMR000151639 | cid_11948738
Type:
Small organic molecule
Emp. Form.:
C22H16N6O
Mol. Mass.:
380.402
SMILES:
Oc1ccc2ccccc2c1CN=Nc1nnc(-c2ncc[nH]2)c2ccccc12 |w:13.15|
Structure:
Search PDB for entries with ligand similarity: