Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84227
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
12100±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84227
Synonyms:
1-[1-[4-(dibutylamino)-6-methoxy-1,3,5-triazin-2-yl]-5-methyl-1,2,3-triazol-4-yl]ethanone | 1-[1-[4-(dibutylamino)-6-methoxy-1,3,5-triazin-2-yl]-5-methyl-4-triazolyl]ethanone | 1-[1-[4-(dibutylamino)-6-methoxy-1,3,5-triazin-2-yl]-5-methyltriazol-4-yl]ethanone | 1-[1-[4-(dibutylamino)-6-methoxy-s-triazin-2-yl]-5-methyl-triazol-4-yl]ethanone | MLS000519549 | SMR000129967 | cid_4393516
Type:
Small organic molecule
Emp. Form.:
C17H27N7O2
Mol. Mass.:
361.442
SMILES:
CCCCN(CCCC)c1nc(OC)nc(n1)-n1nnc(C(C)=O)c1C
Structure:
Search PDB for entries with ligand similarity: