Reaction Details Report a problem with these data
Target
ELAV-like protein 1
Ligand
BDBM50240688
Substrate
n/a
Meas. Tech.
ChEMBL_1668505 (CHEMBL4018393)
IC50
69600±n/a nM
Citation
 Nasti, R; Rossi, D; Amadio, M; Pascale, A; Unver, MY; Hirsch, AKH; Collina, S Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs. J Med Chem 60:8257-8267 (2017) [PubMed]  Article 
Target
Name:
ELAV-like protein 1
Synonyms:
ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R
Type:
PROTEIN
Mol. Mass.:
36102.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_654855
Residue:
326
Sequence:
MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK
  
Inhibitor
Name:
BDBM50240688
Synonyms:
CHEMBL4077803
Type:
Small organic molecule
Emp. Form.:
C27H29NO10
Mol. Mass.:
527.5199
SMILES:
COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CCC(O)C(C)O5)c4c(O)c3C(=O)c12)C(\C)=N\O
Structure:
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