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Target
Carnitine O-palmitoyltransferase 1, muscle isoform
Ligand
BDBM50260105
Substrate
n/a
Meas. Tech.
ChEMBL_1692682 (CHEMBL4043572)
IC50
14000±n/a nM
Citation
 Tseng, CC; Noordali, H; Sani, M; Madhani, M; Grant, DM; Frenneaux, MP; Zanda, M; Greig, IR Development of Fluorinated Analogues of Perhexiline with Improved Pharmacokinetic Properties and Retained Efficacy. J Med Chem 60:2780-2789 (2017) [PubMed]  Article 
Target
Name:
Carnitine O-palmitoyltransferase 1, muscle isoform
Synonyms:
CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b
Type:
PROTEIN
Mol. Mass.:
88241.28
Organism:
Rattus norvegicus
Description:
ChEMBL_887447
Residue:
772
Sequence:
MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPTSWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATGIFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPSVPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEEYVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALGMVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDLEMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVALDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPIIGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGYGVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS
  
Inhibitor
Name:
BDBM50260105
Synonyms:
CHEMBL1592481
Type:
Small organic molecule
Emp. Form.:
C19H35N
Mol. Mass.:
277.4879
SMILES:
C(C(C1CCCCC1)C1CCCCC1)[C@@H]1CCCCN1
Structure:
Search PDB for entries with ligand similarity: