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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM50303910
Substrate
n/a
Meas. Tech.
ChEMBL_1705356 (CHEMBL4056589)
IC50
24000±n/a nM
Citation
 Balti, M; Plas, A; Meinguet, C; Haufroid, M; Thémans, Q; Efrit, ML; Wouters, J; Lanners, S Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase. Bioorg Med Chem Lett 27:3607-3610 (2017) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Homo sapiens (Human)
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM50303910
Synonyms:
4-phenylthiazole-2-thiol | CHEMBL571436
Type:
Small organic molecule
Emp. Form.:
C9H7NS2
Mol. Mass.:
193.289
SMILES:
Sc1nc(cs1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: