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Target
DCN1-like protein 1
Ligand
BDBM50271342
Substrate
n/a
Meas. Tech.
ChEMBL_1711073 (CHEMBL4121122)
Ki
140±n/a nM
Citation
 Zhou, H; Zhou, W; Zhou, B; Liu, L; Chern, TR; Chinnaswamy, K; Lu, J; Bernard, D; Yang, CY; Li, S; Wang, M; Stuckey, J; Sun, Y; Wang, S High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J Med Chem 61:1934-1950 (2018) [PubMed]  Article 
Target
Name:
DCN1-like protein 1
Synonyms:
DCN1 | DCN1-like protein 1 | DCNL1_HUMAN | DCUN1 domain-containing protein 1 | DCUN1D1 | DCUN1L1 | Defective in cullin neddylation protein 1-like protein 1 | RP42 | SCCRO | Squamous cell carcinoma-related oncogene | Synonyms=DCN1
Type:
PROTEIN
Mol. Mass.:
30118.96
Organism:
Homo sapiens
Description:
ChEMBL_117443
Residue:
259
Sequence:
MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV
  
Inhibitor
Name:
BDBM50271342
Synonyms:
CHEMBL4129541
Type:
Small organic molecule
Emp. Form.:
C38H51N5O4
Mol. Mass.:
641.8426
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCCc2ccccc12 |r|
Structure:
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