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Target
DCN1-like protein 1
Ligand
BDBM50271350
Substrate
n/a
Meas. Tech.
ChEMBL_1711073 (CHEMBL4121122)
Ki
54±n/a nM
Citation
 Zhou, H; Zhou, W; Zhou, B; Liu, L; Chern, TR; Chinnaswamy, K; Lu, J; Bernard, D; Yang, CY; Li, S; Wang, M; Stuckey, J; Sun, Y; Wang, S High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J Med Chem 61:1934-1950 (2018) [PubMed]  Article 
Target
Name:
DCN1-like protein 1
Synonyms:
DCN1 | DCN1-like protein 1 | DCNL1_HUMAN | DCUN1 domain-containing protein 1 | DCUN1D1 | DCUN1L1 | Defective in cullin neddylation protein 1-like protein 1 | RP42 | SCCRO | Squamous cell carcinoma-related oncogene | Synonyms=DCN1
Type:
PROTEIN
Mol. Mass.:
30118.96
Organism:
Homo sapiens
Description:
ChEMBL_117443
Residue:
259
Sequence:
MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV
  
Inhibitor
Name:
BDBM50271350
Synonyms:
CHEMBL4128331
Type:
Small organic molecule
Emp. Form.:
C39H47FN6O4S
Mol. Mass.:
714.892
SMILES:
CCC(=O)N[C@@H](Cc1nc2ccc(F)cc2s1)C(=O)N[C@@H](C1CCCC1)C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Structure:
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