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Target
Mitogen-activated protein kinase 1
Ligand
BDBM50271381
Substrate
n/a
Meas. Tech.
ChEMBL_1711153 (CHEMBL4121202)
Kd
>1000000±n/a nM
Citation
 Nagatoishi, S; Yamaguchi, S; Katoh, E; Kajita, K; Yokotagawa, T; Kanai, S; Furuya, T; Tsumoto, K A combination of Bioorg Med Chem 26:1929-1938 (2018) [PubMed]  Article 
Target
Name:
Mitogen-activated protein kinase 1
Synonyms:
ERK2 | ERT1 | Extracellular signal-regulated kinase 2 | Extracellular signal-regulated kinase 2 (ERK-2) | Extracellular signal-regulated kinase 2 (ERK2) | MAP Kinase 2/ERK2 | MAPK 2 | MAPK1 | MK01_HUMAN | Mitogen activated kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK2) | Mitogen-activated protein kinase 2 | PRKM1 | PRKM2 | p42-MAPK
Type:
Ser/Thr Protein Kinase
Mol. Mass.:
41392.76
Organism:
Homo sapiens (Human)
Description:
P28482
Residue:
360
Sequence:
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
  
Inhibitor
Name:
BDBM50271381
Synonyms:
CHEMBL4129762
Type:
Small organic molecule
Emp. Form.:
C13H15FN2O
Mol. Mass.:
234.2694
SMILES:
Fc1ccc2C(=O)N(Cc2c1)[C@H]1CCCNC1 |r|
Structure:
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