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Target
Sigma intracellular receptor 2
Ligand
BDBM321286
Substrate
n/a
Meas. Tech.
ChEBML_1716892
Ki
1400±n/a nM
Citation
 Donnier-Maréchal, M; Carato, P; Larchanché, PE; Ravez, S; Boulahjar, R; Barczyk, A; Oxombre, B; Vermersch, P; Melnyk, P Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands. Eur J Med Chem 138:964-978 (2017) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM321286
Synonyms:
N-(2-(benzyl(methyl)amino)ethyl)-4-nitrobenzamide | US10179761, Compound 3.1.37
Type:
Small organic molecule
Emp. Form.:
C17H19N3O3
Mol. Mass.:
313.3511
SMILES:
CN(CCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Structure:
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