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Target
Interleukin-5
Ligand
BDBM50242276
Substrate
n/a
Meas. Tech.
ChEBML_1717607
IC50
10600±n/a nM
Citation
 Boggu, PR; Venkateswararao, E; Manickam, M; Kim, Y; Jung, SH Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors. Eur J Med Chem 139:290-304 (2017) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50242276
Synonyms:
CHEMBL486626 | Sophoricoside
Type:
Small organic molecule
Emp. Form.:
C21H20O10
Mol. Mass.:
432.3775
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2coc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
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