Reaction Details Report a problem with these data
Target
Vitamin K epoxide reductase complex subunit 1
Ligand
BDBM50015552
Substrate
n/a
Meas. Tech.
ChEBML_214470
Ki
17000±n/a nM
Citation
 Ryall, RP; Nandi, DL; Silverman, RB Substituted vitamin K epoxide analogues. New competitive inhibitors and substrates of vitamin K1 epoxide reductase. J Med Chem 33:1790-7 (1990) [PubMed]  Article 
Target
Name:
Vitamin K epoxide reductase complex subunit 1
Synonyms:
VKOR1_BOVIN | VKORC1 | Vitamin k epoxide reductase complex subunit 1 isoform 1
Type:
PROTEIN
Mol. Mass.:
17977.60
Organism:
Bos taurus
Description:
ChEMBL_305987
Residue:
163
Sequence:
MGATWRSPGWVRLALCLAGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGKDSILNQSNSIFGCIFYTLQLLLGCLQGRWASVLLRLSCLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVGLTVLSFREVQGPQGKVKGH
  
Inhibitor
Name:
BDBM50015552
Synonyms:
7a-Fluoromethyl-1a-(3,7,11,15-tetramethyl-hexadec-2-enyl)-1a,7a-dihydro-1-oxa-cyclopropa[b]naphthalene-2,7-dione | CHEMBL51260
Type:
Small organic molecule
Emp. Form.:
C31H45FO3
Mol. Mass.:
484.6856
SMILES:
CC(C)CCCC(C)CCCC(C)CCC\C(C)=C\CC12OC1(CF)C(=O)c1ccccc1C2=O
Structure:
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