Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50292258
Substrate
n/a
Meas. Tech.
ChEMBL_1731751 (CHEMBL4147287)
Ki
>1000±n/a nM
Citation
 Tuo, W; Bollier, M; Leleu-Chavain, N; Lemaire, L; Barczyk, A; Dezitter, X; Klupsch, F; Szczepanski, F; Spencer, J; Chavatte, P; Millet, R Development of novel oxazolo[5,4-d]pyrimidines as competitive CB Eur J Med Chem 146:68-78 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50292258
Synonyms:
CHEMBL4164392
Type:
Small organic molecule
Emp. Form.:
C16H17ClN4O
Mol. Mass.:
316.785
SMILES:
CCCCCNc1ncnc2oc(nc12)-c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: