Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50292257
Substrate
n/a
Meas. Tech.
ChEMBL_1731752 (CHEMBL4147288)
Ki
>1000±n/a nM
Citation
 Tuo, W; Bollier, M; Leleu-Chavain, N; Lemaire, L; Barczyk, A; Dezitter, X; Klupsch, F; Szczepanski, F; Spencer, J; Chavatte, P; Millet, R Development of novel oxazolo[5,4-d]pyrimidines as competitive CB Eur J Med Chem 146:68-78 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50292257
Synonyms:
CHEMBL4175043
Type:
Small organic molecule
Emp. Form.:
C14H13ClN4O2
Mol. Mass.:
304.732
SMILES:
COCCNc1ncnc2oc(nc12)-c1ccccc1Cl
Structure:
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