Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50369689
Substrate
n/a
Meas. Tech.
ChEMBL_1736931 (CHEMBL4152681)
Ki
212±n/a nM
Citation
 Lambertucci, C; Marucci, G; Dal Ben, D; Buccioni, M; Spinaci, A; Kachler, S; Klotz, KN; Volpini, R New potent and selective A Eur J Med Chem 151:199-213 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50369689
Synonyms:
CHEMBL4173347
Type:
Small organic molecule
Emp. Form.:
C13H13N5
Mol. Mass.:
239.2758
SMILES:
CCn1c(nc2c(N)ncnc12)-c1ccccc1
Structure:
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